An international exchange event on monitoring SARS-COV-2 in wastewater systems was organized from 11-12 November 2021 by GIZ under the Indo-German Development Cooperation project “Support to Ganga Rejuvenation” (SGR) in cooperation with National Mission for Clean Ganga (NMCG). The event was held on a hybrid mode in partnership with Hessen Trade & Invest GmbH, Germany, and supported by Mu Gamma Consultants Pvt. Ltd, India as Consultants. The two-day event included four thematic sessions structured around the themes: Indian and international research developments on wastewater-based-epidemiology (WBE), application of WBE for monitoring SARS-CoV-2 in wastewater, and the policy implications of these research studies specific to the Indian context. The event aimed to facilitate the exchange of the existing knowledge, research, experiences, and application of WBE as an early warning system towards controlling the spread of the virus in specific regions. The speakers included eminent scientists/experts from the European Union, the United States of America, and India. More than 180 participants from various sectors including national and state-level ministries/departments and executing agencies such as State Mission for Clean Ganga, State and Central Pollution Control Boards, Central Water Commission, relevant academicians and researchers, and practitioners from the wastewater monitoring agencies participated in the sessions.